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Gout

Gout: A Foe for your Toe Gout is a misunderstood malady. Despite the intense pain that gout can bring, it is a condition that is rarely makes the glossy pages of a magazine. If you are ever personally hit with the sudden onset of gout, classically (50% of the time) seen as a sudden and excruciating pain in the big toe, you will have a newly found interest in the following information.


However, restricting purines in your diet is not difficult, so it is still worth doing. The conventional wisdom may be correct. Uric acid level tests should tell if a low purine diet works for you.


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 Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder. Rheumatoid arthritis occurs when the body's defence mechanisms go into action when there's no threat and start attacking the joints and sometimes other parts of the body. RA affects 2.1 million Americans, or about 1% of the adult population in the United States. This disease is 2 to 3 times more common in women than in men, and generally affects people between the ages of 20 and 50. However, young children can develop a form of RA called juvenile rheumatoid arthritis. Two of the 100 types of arthritis are rheumatoid arthritis and lupus. There are specific symptoms, distinguishing characteristics, as well as overlapping symptoms associated with rheumatoid arthritis and lupus. Rheumatoid arthritis is an additive polyarthritis, with the sequential addition of involved joints, in contrast to the migratory or evanescent arthritis of systemic lupus erythematosus or the episodic arthritis of gout. Occasionally, patients experience an explosive polyarticular onset occurring over 24 to 48 hours. Morning stiffness, persisting more than one hour but often lasting several hours, may be a feature of any inflammatory arthritis but is especially characteristic of rheumatoid arthritis. Its duration is a useful gauge of the inflammatory activity of the disease.

THE CAUTION Rapid changes in uric acid levels can trigger a gout attack. This rapid change can be brought about by many factors in addition to possibly mega doses of Vitamin C and by drugs such as probenecid and sulfinpyrazone. People who are susceptible to gout must consider these rapid changes.

A few studies over the past 30 years have concluded that Vitamin C will reduce the uric acid level. They have differed in the amount of Vitamin C given to study participants. A U.S. study of 184 non-smokers, published in 2005, concluded that the amount required to achieve a serum (blood) uric acid level reduction was 500 mg daily. (The Vitamin C was taken as a supplement). This is not a mega dose.

Gout is caused by elevated levels of uric acid in the fluids of your body. These uric acid crystals deposit in joints, tendons and kidneys, damaging the tissues and causing inflammation and pain. The pain is a result of countless needle-like crystals that form from the excess uric acid.

OTHER FACTORS There are many factors to consider with regards to arthritic diets and nutritional healing, and each factor may not apply to each individual. For example, certain people are allergic to specific foods, and these allergies can indeed worsen arthritic conditions. Ingesting foods that contain sodium nitrate or tartrazine can inflame rheumatoid arthritis, while ingesting foods containing a substance called hydrazine can contribute to systemic lupus erythematosus, an arthritic condition connected to lupus. There is a rare type of arthritis called Behcet's Disease, and eating black walnuts can cause flare-ups in people with this rare condition. So as you see, there is a variety of arthritic conditions and along with them a variety of foods that may trigger them. The best way to approach the situation is to examine each arthritic condition and tailor one's approach based upon the specifics.

Previously it has been thought that the amount needed was at least 4,000 mg (4 grams) daily. For example, Dr. Robert Atkins in his book " Vita Nutrient Solutions," recommended 5,000 -10,000 mg as part of his formula natural remedy for gout.

However, gout sufferers are overwhelmingly (95%) male.

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VITAMIN C AS A GOUT PREVENTOR If 500 mg daily of Vitamin C can reduce uric acid levels, then Vitamin C ought to act as a preventative gout vitamin too. A Taiwan study of males in the late 1990's examined the weight, diet and lifestyles of gout and non-gout sufferers in Taiwan. It concluded that Vitamin C, folic acid (folate) and fibre were protective against gout.

It also reached the well-known and accepted conclusion that hypertension (high blood pressure) and obesity are risk factors for gout. And one other very different conclusion from the conventional wisdom about purines -- purine intake, with the exception of alcohol, was NOT associated with a risk of gout.

Conventional treatment for the symptoms of gout is the anti-inflammatory drug colchicine. Isolated from the autumn crocus, colchicine has a strong effect to combat inflammation (though it has no effect on uric acid levels!). This provides most sufferers relief within the day, although the drug may be difficult for many to tolerate due to digestive side effects.

Should you take Vitamin C for gout? The answer is probably yes, but read on for a possibly relevant caution. Gout cures require that uric acid levels be reduced. Vitamins and drugs work in two ways to reduce uric acid levels. One is restricting its supply by inhibiting purine breakdown into uric acid, the other is improving uric acid's breakdown into the urine. Vitamin C is thought to be a uric acid excretory, not an inhibitor. Improving excretion may be more important than reducing production.

Septic arthritis also known is Pyogenic arthritis. Septic arthritis is infection, usually bacterial, in the joint cavity. Septic arthritis usually affects just one joint, though occasionally it may occur in more than one joint at a time. It is the most dangerous form of acute arthritis. The joint cavity is usually a sterile space, with synovial fluid and cellular matter including a few white blood cells. Many different types of bacteria (germs) can cause septic arthritis. Infection with a bacterium called Staph. aureus is the most common cause. Septic arthritis is inflammation of a synovial membrane with purulent effusion into the joint capsule, usually due to bacterial infection. This disease entity also is referred to in the literature as bacterial, suppurative, purulent, or infectious arthritis. The most common bacterial isolates in native joints include gram-positive cocci, with S. aureus found in 40% to 50% of the cases. Septic arthritis is uncommon from age 3 to adolescence. Children with septic arthritis are more likely than adults to be infected with group B streptococcus and Haemophilus influenza. Young children and older adults are most likely to develop septic arthritis. As the population ages, doctors are finding that septic arthritis is becoming more common. Symptoms of septic arthritis occur suddenly and are characterized by severe pain, swelling in the affected joint along with acute pain. Chills and fever are also common symptoms. Chronic septic arthritis (which occurs less frequently) is caused by organisms such as Mycobacterium tuberculosis and Candida albicans. The knee and the hip are the most commonly infected joints.

To prevent gout attacks, the following lifestyle should be considered: ' Avoid alcohol, a major influence in initiating attacks. ' Follow a low-purine diet. This includes organ meats, meat, shellfish, yeast, and sardines, mackerel, etc. ' Reduce excess food intake including processed carbohydrates, excess fat and excess protein.

Gout is one of the most painful types of arthritis. Gout was once incorrectly thought to be a disease of the rich and famous, caused by consuming too much rich food and fine wine. Gout is a disease due to a congenital disorder of uric acid metabolism. Uric acid is produced when purines are broken down by enzymes in the liver. Purines can be generated by the body itself (via the breakdown of cells in normal cellular turnover) or can be ingested in purine-rich foods (e.g. seafood, beer). Gout usually attacks the big toe (approximately 75% of first attacks), however it can also affect other joints such as the ankle, heel, instep, knee, wrist, elbow, fingers, and spine. In some cases the condition may appear in the joints of the small toes which have become immobile due to impact injury earlier in life, causing poor blood circulation that leads to gout. Chronic gout can lead to deposits of hard lumps of uric acid in and around the joints, decreased kidney function, and kidney stones. An acute attack of gout is a highly inflammatory arthritis often with intense swelling, redness and warmth surrounding the joint. The inflammatory component is so intense, an acute attack of gout is often mistaken for a bacterial cellulitis. Gout is mainly treated with anti-inflammatory drugs. Corticosteroids (also called steroids), may be prescribed for people who cannot take NSAIDs. Steroids also work by decreasing inflammation. Steroids can be injected into the affected joint or given as pills. Colchicine is often used to treat gout and usually begins working within a few hours of taking it.

One complicating factor is that elusive fact that most people with hyperuricemia (excess uric acid)do not get gout. Another is that some people with normal uric acid levels do.

1,000 MG PLUS DOSES If you wish to try Vitamin C for gout in doses over 1,000 mg as part of a natural gout remedy discuss it with your doctor or a qualified naturopathic doctor. The 500 mg level is below the British government's 1,000 mg (1 gram) recommended upper safety level safety limit for Vitamin C. It is half of the maximum amount (1,000 mg) in a Vitamin C tablet sold in the U.S. and many other countries.

 
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Psoriatic arthritis is related to the skin condition psoriasis. It occurs more commonly in patients with tissue type HLA-B27. There are five clinical patterns of psoriatic arthritis. First is Asymmetrical mono- and oligoarticular arthritis (30-50% of cases) is the most common presentation of psoriatic arthritis. Second is symmetrical polyarticular arthritis (30-50% of cases) is ultimately the most common form of psoriatic arthritis. Third is distal interphalangeal (DIP) joint involvement (25% of cases) is nearly always associated with nail manifestationsm. Fourth is Arthritis mutilans is affects less than 5% of patients and is a severe, deforming and destructive arthritis. This condition can progress over months or years causing severe joint damage. Fifth is Axial arthritis (30-35% of cases) may be different in character from ankylosing spondylitis, the prototypical HLA-B27-associated spondyloarthropathy. It may present as sacro-iliitis, which may be asymmetrical and asymptomatic, or spondylitis, which may occur without sacro-iliitis and may affect any level of the spine in "skip" fashion. Genetic factors appear to play an important role. There is a 70% concordance for psoriasis in monozygotic twins. There is a 50-fold increased risk of developing psoriatic arthritis in first-degree relatives of patients with the disease. Environmental factors have been implicated. Streptococcal infection can precipitate the development of guttate psoriasis. HIV infection can present with both psoriasis and psoriatic arthritis, as well as worsen existing disease.

Arthritis is a disease that causes pain and loss of movement of the joints. Joint pain is referred to as arthralgia. Arthritis is the leading cause of disability in people over the age of 55. The causes of arthritis depend on the form of arthritis. Causes include injury (leading to osteoarthritis), abnormal metabolism (such as gout and pseudogout), inheritance, infections, and for unclear reasons (such as rheumatoid arthritis and systemic lupus erythematosus). There are many forms of arthritis .There are about 200 different kinds of arthritis. The most common type is osteoarthritis (or degenerative arthritis), where the cartilage that protects the bones gets worn away. This makes joints stiff, painful and creaky. About 5 million people in the UK have osteoarthritis. OA is a chronic degenerative arthropathy that frequently leads to chronic pain and disability. With the aging of our population, this condition is becoming increasing prevalent and its treatment increasingly financially burdensome. Using radiographic criteria, the distal and proximal interphalangeal joints of the hand have been identified as the joints most commonly affected by OA, but they are the least likely to be symptomatic. Age is the most consistently identified risk factor for OA, regardless of the joint being studied. Prevalence rates for both radiographic OA and, to a lesser extent, symptomatic OA rise steeply after age 50 in men and age 40 in women. Occupation-related repetitive injury and physical trauma contribute to the development of secondary (non-idiopathic) OA, sometimes occurring in joints that are not affected by primary (idiopathic) OA, such as the metacarpophalangeal joints, wrists and ankles.

There is a great deal of debate in the medical world about the effects of overall diet on arthritis and using diet toward alleviating the condition. Doctors have known for a long time that diet affects gout, a specific type of arthritic condition, however the jury remained out for a long time on other common types of arthritis such as rheumatoid and osteoarthritis. However, overall dietary health is important and does come into play. Being overweight can affect certain arthritic conditions, forcing some joints to carry more of a load. This added weight stresses the joints, causing overuse or more wear to components, and pain, especially in the knees. So making sure arthritic sufferers eat god foods and get help from healthcare providers to create and follow a well-balanced dietary plan is advised. To begin, here is a look at some vitamins, minerals, nutrients / foods and some herbal applications to consider. VITAMINS Vitamin B5 - When grouped and tanked together, B vitamins work at their peak. They, and B5 specifically, are good for reducing swelling. Vitamin B3 - This vitamin reduces tissue swelling and dilates small arteries, increasing blood flow. Note that Vitamin B3 is NOT advised for persons with high blood pressure, gout or sliver disorders. Vitamin B6 - Another B that reduces tissue swelling. Vitamin B12 - This vitamin aids in multiple functions. It helps with cell formation, digestion, myelin production, nerve protection. Vitamin C - This vitamin acts as an anti-inflammatory, relieving pain, and rids the body of free radicals. Vitamin E - This is a strong antioxidant that protects joints from free radicals while increases joint flexibility. Vitamin K - This vitamin assists with mineral deposit into the bone matrix.

In the 2005 study by how much did 500 mg of Vitamin C reduce their uric acid level? It found an average, across all participants, reduction of about 10% (0.5 mg/dL). In addition, reductions were larger among participants who had higher levels of uric acid at the start of the study. Participants took the 500 mg daily level for two months. Those who were given a placebo (i.e. not Vitamin C) showed a slight increase in uric acid levels.

0.5 mg/dL is a useful reduction but for most people probably not a natural remedy for gout, although the 0.5 mg/dL figure is an average and some participants did better. But a 0.5mg/dL reduction will not be enough to reduce uric acid below the 6.0 mg/dL level at which the MSU crystals may dissolve. However, when combined with other vitamins for gout, a low purine diet and other natural remedies for gout, it could be.

The first sign of gout is usually an intense pain during the night. The attack is commonly brought on following a day or evening of excess in alcohol, food, some drugs, or surgery. If the attack progresses, fever and chills will follow. Recurring attacks are common (90%), mostly occurring in the first year. While chronic gout is quite rare, gout sufferers do have a higher risk of kidney dysfunction and kidney stones.

If you take Vitamin C for gout as a dietary supplement, remember that it is reckoned to work better in a product that contains added citrus bioflavonoids. In addition, because it is excreted quickly, take it twice daily. To avoid excess acidity (lower pH) also take alkalizing minerals, or another alkalizing agent recommended by your doctor.

There are two main types of gout, primary and secondary. Most (90%) of gout sufferers fall into the 'primary' category. This is a pattern with a cause that is generally unknown (idiopathic), although there are some genetic patterns that can lead one to tend toward elevated uric acid. Secondary gout is identified when uric acid is elevated in response to some other disorder (such as kidney disease). Some medicines (such as aspirin and diuretics) can lead to the onset of gout attacks because they decrease the excretion of uric acid from the body.

Such a rapid change concerned the authors of one study in the 1970's who had recorded that mega doses of Vitamin C (4,000 mg and 8,000 mg daily) reduced uric acid levels significantly, and by more than in the 2005 study. However, as far as Vitamin C induced changes in uric acid levels is concerned, this triggering has not been reported in any study.

MINERALS Boron - This trace mineral aids in bone health. Calcium - This is a much-needed mineral for bone health. Magnesium - Magnesium helps keep calcium in balance within the system. Zinc - This mineral is necessary for bone growth, but is often lacking in arthritic patients. Manganese - Manganese is also necessary for bone growth. However, do not ingest manganese with calcium because they can work against each other. Copper - Copper helps to strengthen connective tissue. Germanium - This antioxidant helps with pain relief. Sulfur - A lack of sulfur can result in deterioration of ligaments, cartilage, collagen and tendons. NUTRIENT COMBOS Chondroitin Sulfate - This lubrication in joints, joint fluid and connective tissue, can be found in the sea cucumber. Gelatin - Help with raw cartilage replenishing with this cheap source. Glucosamine Sulfate - This combo is necessary for tendon, ligament, bone, cartilage, and synovial (joint) fluid formation. Quercetin - This helps with inflammation reduction. Type II Collagen - Use this for growth and repair of joints, articular cartilage and connective tissue.

About the author:
Dhiraj Bhikoo is an href="http://www.arthritis-pain-relief-and-treatment.com" target="_blank">arthrit
is pain relief and treatment researcher .He offers advice
and tips and a broad range of alternative solutions for
arthritis and pain related issues.

If you find yourself or your loved one suffering from a gout attack, it is unlikely you would hesitate to seek professional help. The pain of an acute gout attack has been compared to the pain of childbirth.

Juliet Cohen writes articles for http://www.health-care-articles.info/ and http://www.healthatoz.info/


 
 
     
 
 





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