mechanism of action of colchicine - Arthritis - Herbs and Ayurvedic Remedies, Arthritis Symptom and other Treatments
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Arthritis - Herbs and Ayurvedic Remedies, Arthritis Symptom and other Treatments

What is Arthritis? Arthritis is inflammation of the joints. It can occur anywhere in the body and, based on that, there are several types of arthritis. The most common type of arthritis is osteoarthritis which is the common ailment of pain in the joints observed in elderly people. Other common types of arthritic ailments are rheumatoid arthritis and gout.


Treatment: To real treatment of gout starts with ensuring that all the orifices of the body, which expel waste and morbid matter, are activated to do their work properly. The patient should breathe fresh air, so that oxygen is available to him in larger quantities cleansing his blood of poisonous humours. The gout patient must increase his intake of water to produce more urine. He should take lukewarm water in the morning and evening mixed with the juice of mine. The pores of the skin should be activated by a cold bath every day and drying of the body with vigorous rubbing with the palms of the hand. If the pain in the joints is too severe and the patient is unable to massage his body himself, he should seek somebody else's help. Sun bathing should be undertaken to produce sweat. The head may be covered with a wet towel to save it from excessive heat of the sun. Spending half an hour in the sun will activate the sweat glands. A cold bath is recommended after a sunbath; if the patient does not feel equal to it, he would be better advised to wipe his body with a wet towel. Sun bathing should be done no more than thrice in a week. If there is no sun, sweat should be induced by a steam bath or by merely soaking one's feet in hot water.


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 (2) Rheumatoid Arthritis - Rheumatoid arthritis is a more serious problem than osteoarthritis because it can occur at any age. In people with rheumatoid arthritis, the ligaments and tendons between the joints undergo degeneration. This causes severe pain where the degeneration has taken place. Common rheumatoid arthritis pains are felt in the fingers; but other places like the wrists, hip and knees are also affected. Rheumatoid arthritis is responsible for deformation of the fingers.

Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts.

Key Terms

Fanconi's syndrome
A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
Gout
A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
Hyperuricemia
Excessively high levels of uric acid in the blood, often producing gout.
Purine
A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Uric acid
A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
Uricosuria
Increased levels of uric acid in the urine.
Wilson's disease
A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.

Further Reading

For Your Information

    Books

  • Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
  • Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
  • Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.

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If you have recurrent pains in the joints, then do not keep the joint covered. As far as possible, keep the joint exposed to the air. For example, if you have pain in the knee joints, then do not wear tight denim clothing; shorts would be a good idea. This will provide freer circulation of blood in the joint and reduce the pains.

Hot fomentation should be undertaken to reduce the pain in the joints. About 75 grammes of salt should be added to one litre of hot water for fomentation. The site of fomentation should be washed with cold water later on. Those who suffer from a constant pain should apply a paste of raw potatoes ground fine on the affected joints. The paste should be allowed to remain for some hours.

Risks

Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded.

Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout.

(3) Septic Arthritis - Septic arthritis is a special type of arthritis which is caused when the joints get infected. (4) Gout - Gout is common old-age arthritis. It is caused when crystals of uric acid are deposited in the spaces between the joints. This type of arthritis is linked with faulty digestion.

Hippo crates in his Aphorisms speaks of gout as occurring most commonly in spring and autumn, and mentions the facts that women are less liable to it than men. Why the uric acid is found in excess is not understood by the allopathic physicians. Uric acid is formed in the system in the process of nutrition and is excreted by the kidneys. In a patient suffering from gout, the quantity of uric acid is found to be much more than normal. In a paroxysm of gout, the body appears to get rid of a lot of uric acid and there appears to be some relied but that is purely temporary.

The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.

Overview of Gout Gout is a systemic disease caused by the buildup of uric acid in the joints, causing inflammation, swelling, and pain. This condition can develop for two reasons. The liver may produce more uric acid than the body can excrete in the urine, or a diet of rich foods (e.g., red meat, cream sauces, red wine) puts more uric acid into the bloodstream than the kidneys can filter. In both cases, a condition called hyperuricemia results. Over time, the uric acid crystallizes and settles in the joint spaces, most commonly in the first metatarsal phalangeal joint of the big toe or in the ankle joint. Signs and Symptoms The most common symptoms of gout are inflammation, swelling, and tenderness in the joint of the first toe. Touching or moving it is intensely painful and patients often say it hurts to have as much as a bedsheet over the toe. Gout develops quickly and typically occurs in only one joint at a time. Symptoms may develop in two or three joints simultaneously, but this is rare. If widespread symptoms occur, the condition is probably not gout. Diagnosis The most reliable way to diagnose gout is to examine the joint fluid for uric acid crystals. This is done by drawing fluid from the joint with a needle and examining it under a polarized light microscope. Although the test is invasive, the results are definitive, and a positive result facilitates proper treatment and quick relief. Treatment Treatment for gout involves decreasing the amount of uric acid in the joint. If dietary habits are the cause, the patient's lifestyle must be changed to avoid the condition. Gout is readily corrected with patient cooperation, and it is usually not treated unless it occurs frequently. Colchicine is a common medication for treating acute gout attacks. If continuous medication is necessary, the two most common choices are probenecid and allopurinol. Prevention Alcohol and rich foods are primary contributors to excessive uric acid levels. Although some patients have a genetic predisposition to excessive uric acid production, most gout patients have normal kidneys and uncontrolled dietary habits. Prevention is the best defense against the disease. Many patients who suffer from gout continue to indulge, and suffer frequent attacks as a result. Although medication makes it possible to live with gout, the continued accumulation of uric acid in the joints eventually damages them, seriously inhibiting movement.

The word arthritis is derived from two root Greek words - arthros meaning 'joint' and it is meaning 'inflammation'. Hence, arthritis literally translates as inflammation of the joints.

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The disease is more common in mature age and in the males than females. Persons exposed to the influence of lead poisoning such as plumbers, are apt to suffer from gout. Attacks of the disease are readily excited by exposure to cold, disorders of indigestion, fatigue and injuries to particular joints.

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An attack of gout may appear without warning, or there may be premonitory symptoms. Among the most common of these are disorders of the digestive organs, with a feeble and capricious appetite, flatulence, uneasiness in the right side in the region of the liver, and irritation in the urinary organs. There is also irritability, numbness and coldness in the limbs. The attack comes usually at night, usually between two and three in the morning. The affected part is found to be swollen and a deep red hue. The skin is tense and glistening and the surrounding veins are more or less distended. The attack lasts for a week or ten days during which the patient suffers from constipation, dyspepsia and extreme thirst. The urine is scanty and high coloured with a copious deposit, consisting chiefly of urates. The joint affected may become swollen but if the disease is not attended to, the swelling spreads to other joints and it becomes chronic. Joints also become enlarged and refuse to function without giving excruciating pain to the sufferer.

 
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Precautions

Blood test

Patients scheduled for a blood test for uric acid should be checked for the following medications: loop diuretics (Diamox, Bumex, Edecrin, or Lasix); ethambutol (Myambutol); vincristine (Oncovin); pyrazinamide (Tebrazid); thiazide diuretics (Naturetin, Hydrex, Diuril, Esidrix, HydroDiuril, Aquatensen, Renese, Diurese); aspirin (low doses); acetaminophen (Tylenol); ascorbic acid (vitamin C preparations); levodopa (Larodopa); or phenacetin. These drugs can affect test results.

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If in doubt, or if you have questions, you should consult your physician and, if possible, consult a second physician for a possible different opinion. The author does not bear any responsibility for your decisions nor for the outcome of your actions based upon those decisions.

After a five-day period during which only fruits and vegetables are taken, milk should be added to the diet. It should preferably be boiled and taken in quantities of 250 to 500 millilitres at one time. Bread should be taken only after a fortnight of living on fruits and vegetables. Potatoes can replace bread with advantages as they contain more alkaline matter.

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?? Mix some cardamom in milk. Put a pinch of turmeric in this milk. This is to be drunk every night while going to sleep. This makes the person sleep peacefully in the morning.

Urine test

Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified.

The following foods must be avoided if you have continuous arthritic pains:- ?? Animal fats ?? Fried foods ?? Foods rich in carbohydrates like potatoes

Modern medicine believes gout to be hereditary since it has been found in 50 to 80 percent of the cases that the patient's parents or grand parents suffered from the disease. The disease affects the sedentary persons more than those who lead active lives, but it is not always true. On the other hand, inadequate exercise, a luxurious manner of living, habitual over-indulgence in rich foods and especially in alcohol is the precipitating factors in the onset of the disease. Some teetotalers and vegetarians are also found to be victims of gout.

How can Arthritis be controlled with Simple Home Remedies? Some household remedies are known to provide relief from arthritic pains. The following are some of the more benefiting ones:-

The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood.

This article is Copyright 2005 by http://www.organicgreens.us, http://www.organicgreens.ca and Loring Windblad. This article may be freely copied and used on other web sites only if it is copied complete with all links and text, including the Authors Resource Box, intact and unchanged except for minor improvements.

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Overview of Diabetes New to diabetes? Learn the basics ' check with your local diabetes clinic or research it on the internet. A key to diabetes management is maintaining a regular exercise program. Its never too late to start ' see below. Sticking to dietary goals while eating out also can be very challenging ' see comments below. 20 million Americans and Canadians have diabetes. Nearly 7 million don't know it. Type 2 diabetes usually develops slowly, and the symptoms often go unnoticed. Our son developed a puffiness to his face which we noticed right away because we saw him only a couple of times a year. He and his wife put it down to simple weight gain. After 2' years they finally snapped to there being something wrong and when he was finally checked out his diabetes was 'off the charts'. Fortunately, they caught it in time, but it should have been caught over a year earlier. Nearly 90 to 95% of all people with diabetes have type 2. Who gets it? Just about any body. Fat, skinny, regular build, it makes no difference; just about everyone can develop diabetes. Most at risk are people regardless of body build who live on a high intake of 'junk food'. Least at risk are people who eat a regular balanced diet.

Urine test

Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours.

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Preparation

The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.

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Arthritis is an auto-immune disease, which means, it is a disease in which the human body attacks itself. It begins in one or two joints where an acute pain is felt. This is the most miserable phase of arthritis. Over time, this pain may disappear, but it could cause permanent deformities in the bones and joints.

Abnormal results

The critical value for the blood test is a level of uric acid higher than 12 milligrams per deciliter (about 3.4 ounces).

Causes and Symptoms: Gout is a disease of the joints and is a form of rheumatism. It is a constitutional disorder connected with excess of uric acid in the blood manifesting itself by inflammation of joints with deposition of urate of soda and also by morbid changes in various important organs.

Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome.

Why is Arthritis caused? Different types of arthritis are caused due to different reasons. (1) Osteoarthritis - Osteoarthritis is a common old-age problem, which affects several people who have crossed the age of 40 years. In people with osteoarthritis, the bones may increase in size at their articulating points. As a result the spaces between them in the joints become less. When moving about, there is a high probability that different bones will rub against each other. This is the cause of osteoarthritis.

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