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Uric Acid Testing

Definition

Uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine.

Purpose




The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.


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Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts.

Description

The uric acid blood test is performed on a sample of the patient's blood, withdrawn from a vein into a vacuum tube. The procedure, which is called a venipuncture, takes about five minutes. The urine test requires the patient to collect all urine voided over a 24-hour period, with the exception of the very first specimen. The patient keeps the specimen container on ice or in the refrigerator during the collection period.

Other links between sleep apnea and gout include show up in the fact that not only are primary gout sufferers demographically the same as the primary sleep apnea sufferers (middle-aged, overweight men), but sleep apnea and gout are also both much more common among women who have been through menopause. Also, both gout and sleep apnea are associated with people who have a larger neck circumference.

You see, doctors often prescribe medications that keep you coming back! You get a painful gout attack and you get medications to take the pain away. And this cycle will continue until you learn how to naturally lower your uric acid levels. But our metabolic arthritis and gout natural cures aim to prevent gout by decreasing the cause of gout! You can heal yourself completely!

Here are 5 Gout Remedy Tips you can try today! 1. Acid and Alkaline! Uric acid is the cause of gout! And if you neutralize the acids you can actually lower the frequency of the gout flair ups. A good way to do this is through a simple basic or alkaline ingredients. Take a half teaspoon of baking soda, which is a base, and mix it with a glass of water. Drink 3 glasses of this mixture a day during flare-ups!

Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome.

Normal results

Blood test

Reference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly.

The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood.

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Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy.

This effect is very similar to what happens within the cells when excess alcohol is consumed. And it should be noted that drinking alcohol can cause sleep apnea to become more pronounced. Therefore, gout sufferers with sleep apnea have two major reasons to avoid drinking alcohol.

The reason for this link is believed to be the reduction in blood oxygen during apnea episodes, causing cell disintegration in the body and the generation of uric acid in the bloodstream. The cause of gout is, after all, the presence of uric acid crystals in the joints. Furthermore, during apnea there is an increase in the carbon dioxide percentage within the blood, making the blood's acidity level higher and increasing the risk of uric acid precipitation as monosodium urate. This can collect in the joints and can even lead to an increased risk of developing kidney stones.

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The holistic treatments are new to the western world; however, these remedies have been around for centuries. Curing Gout Holistically

There are many different potential triggers for gout that you should be aware of if you suffer from the condition. One of the potential triggers that we've been asked about recently is sleep apnea. It may seem as though these two conditions are completely unrelated, but in reality, they are connected. The connection was first noticed when sleep apnea patients received treatment for their disorder and they noticed their gout symptoms simultaneously improved.

Key Terms

Fanconi's syndrome
A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
Gout
A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
Hyperuricemia
Excessively high levels of uric acid in the blood, often producing gout.
Purine
A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Uric acid
A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
Uricosuria
Increased levels of uric acid in the urine.
Wilson's disease
A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.

Further Reading

For Your Information

    Books

  • Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
  • Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
  • Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.

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Precautions

Blood test

Patients scheduled for a blood test for uric acid should be checked for the following medications: loop diuretics (Diamox, Bumex, Edecrin, or Lasix); ethambutol (Myambutol); vincristine (Oncovin); pyrazinamide (Tebrazid); thiazide diuretics (Naturetin, Hydrex, Diuril, Esidrix, HydroDiuril, Aquatensen, Renese, Diurese); aspirin (low doses); acetaminophen (Tylenol); ascorbic acid (vitamin C preparations); levodopa (Larodopa); or phenacetin. These drugs can affect test results.

Abnormal results

The critical value for the blood test is a level of uric acid higher than 12 milligrams per deciliter (about 3.4 ounces).

Diagnosing a gout case can be very difficult sometimes. However, there are a few procedures that will help your doctor diagnose gout. Here are some of the medical investigations that you doctor will suggest ti diagnose gout: - a blood test is maybe the first procedure that has to be made in diagnosing gout; a blood test can measure the urate level that you have in your blood; urate is the main cause of gout; however, a person can still have high urate levels in his/ her blood and still not suffer from gout; when raised levels of urate appear in the blood, this can indicate that you have gout, but this can also be caused by other medical conditions or medication that a person takes; furthermore, a person can have normal levels of urate in his/ her body during a gout attack; - after a blood test that can give doctors an idea whether you can have gout or not, to be more sure and to be able to diagnose a gout case, doctors will examine the fluid that is found in your joints; this fluid can be extracted from your joints with the help of a needle; this can show you if indeed you suffer from gout or not; the fluid is then looked at under a microscope and if there are urate crystals( they indicate gout) , then they will be spotted right away; if indeed these crystals of urate are found in your joints, then, the blood test was right and you actually suffer from gout; this examination is not at all painful and it is very useful if your gout case starts very unusual; for example, a gout case can sometimes be mistaken for another rheumatic disease, like rheumatoid arthritis and gout can mimic this diseases very well; - another investigation that can be made to diagnose a gout case is x- ray; x- rays of your joints can betaken to see whether you suffer from gout or not, but unfortunately in most of the cases, everything will appear normal and your doctor will not be able to tell if you have gout or not;

 
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Urine test

Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours.

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Gout is a form of rheumatism that can also lead to arthritis. It is a very painful medical condition that mostly affects men of all ages. Gout can also be found in women, but mostly those who have reached menopause.

In fact, many doctors prescribe pharmaceutical NSAIDs and also suggest various natural remedies that were once only found in the eastern world!

Urine test

Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified.

Preparation

The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.

Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood. This condition is called hyperuricemia. Supersaturated uric acid in the urine (uricosuria) can crystallize to form kidney stones that may block the tubes that lead from the kidneys to the bladder (the ureters).

No matter the final remedy, improvements to a patients sleep apnea problem ensures that blood oxygen levels remain high, minimizing uric acid and monosodium urate precipitation and therefore gout flare ups.

The Internet Guide: Gout - http://gout.smartadsscrets.com The Internet Guide: Purines - http://gout.smartadssecrets.com/purines

After suffering with gout for years, Paul finally decided to try some metabolic arthritis and gout natural cures because of a friend's recommendation. The only bad part of his decision is that he waited over 3 years to listen to his friend. The goods news is that Paul is gout free and has permanently cured metabolic arthritis (also called gout) with simple natural cures.

5. Exercise- How could you ever exercise with the pain of gout? You can and it will actually help to break up the uric acid crystals. Begin by taking a 20 minute walk a day to become healthy again. By the way, maintaining a healthy weight will also help you be gout free.

Risks

Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded.

Gout Natural Cures Your Doctor Might Mention We've helped thousands of sufferers cure gout and there is one thing that applies to all of them, "The only way to cure gout is to prevent it from ever occurring!"

And millions of other gout sufferers are also choosing to treat this painful form of arthritis with a holistic treatment that is the most effective remedy on the market. And if you don't know what holistic treatment is?

Holistic treatments are a fancy word for treating an ailment (gout) with a 'whole' body approach. In other words, you are allowing the body along with the right tools (vitamins, herbs, supplements, nutrition, or diet) to cure the problem.

Nicknamed the king of all diseases for the simple fact that many past century kings were often diagnosed with the arthritis of the big toe, also known as gout! Since, NSAIDs weren't around hundreds of years ago, King's had to remedy the arthritis with other means. Holistic medicine was born!

Most notably, though, is that gout attacks are the most common while asleep, indicating that sleep has an impact on gout attacks and sleep disturbances and conditions may also influence the causes of gout attacks.

3. Flushing Uric Acid- There are two great ways to naturally flush the high levels of uric acid in your body! One way is to always drink 12 glasses of water per day. Water will dilute and flush your body of toxins, impurities and uric acid. The second way would be to consume high levels of fruits and vegetables which also flush the body.

2. Food Therapy- Stop eating like a king. These foods should be avoided because they contain high levels of purines which cause gout: red meats, fish, scallops, shellfish, beans, peas, and even alcohol. Our Gout Remedy Report shares what foods you should be eating.

Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout.

If you are intersted in finding more information about gout you can click on this website http://www.gout-info-center.com. Also you will find there valuable information about gout treatments and gout diet.

If you've suffered from a gout attack or two now is the time to take action to stop the attacks in their tracks and discover effective preventative steps before your uric acid levels get out of hand.

The treatments for sleep apnea include preventative actions, such as avoiding sleeping on one's back. When sleeping on the back, the airway can become constricted and is more likely to close, causing the oxygen levels in the blood to be lower than in other sleeping positions. Therefore, changing the way you sleep can help to prevent gout attacks simply by increasing the overall blood oxygen level. Other sleep apnea treatments can include a pressurized CPAP mask or surgery.

So, if you're suffering from gout, you may want to check to make sure that you are not also suffering from sleep apnea, as it may be one of the causes of gout aggravations in your body. Then you will be able to look into both sleep apnea treatments and remedies for the gout itself. Speak to your physician about undergoing a sleep study to determine if you have sleep apnea or not.

4. Eastern Herbs- Alfalfa is an excellent choice to help neutralize high uric acid levels. In addition to its high source of minerals and nutrients, alfalfa has been shown to help dramatically reduce uric acid. There are also 7 other common herbs which reduce the risk.

Until recently, gout and sleep apnea have been treated separately. However, many sleep apnea patients who implement treatments for that condition find that their gout improves at the same time.

If you wish to learn more about Gout, Purines, or Uric Acid, check out Steve's s The Internet Guides. The Internet Guide: Uric Acid: http://gout.smartadssecrets.com/uric_acid

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